Pharmacognosy Magazine, Vol 17, Issue 74, Apr-Jun 2021

Recent Articles

Graphical representation showing comparative antioxidant activity by 2, 2‑ diphenyl‑1‑picrylhydrazyl and 2, 2’‑ azino‑bis (3‑ethylbenzothiazoline‑6‑sulfonic acid) method
Original Article

Characterization of secondary metabolites in different parts of Ocimum gratissimum L. by in vitro antioxidant activity and high-performance liquid chromatography–diode-array detector analysis

Sharmistha Ganguly,yoti Kumar,Tapan Seal

Pharmacognosy Magazine,17(74):209-215
DOI: 10.4103/pm.pm_550_20
Published: July 12, 2021
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The core target interleukin‑6, interleukin‑10 and JAK2/STAT3 signaling pathways in atherosclerosis for curcumol treatment
Original Article

Therapeutic targets and biological mechanisms of curcumol on atherosclerosis: A study based on network pharmacology approach and biological studies

Baolian Ma,Shilin Yang,Junmao Li,Zhiqi Wen,Hui Ouyang,Wugang Zhang,Yulin Feng,Mingzhen He

Pharmacognosy Magazine,17(74):216-222
DOI: 10.4103/pm.pm_336_20
Published: July 12, 2021
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Qualitative analysis of Amomi fructus from different grades based on principal component analysis. (A1), (A2), (A3), and (A4) were Grade A samples; (B5) and (B6) were Grade B samples; (C7) and (C8) were Grade C samples
Original Article

Rapid qualitative and quantitative analysis of volatile components and quality identification of amomi fructus based on bionic olfactory system

Huaying Zhou,Zhong Li,Dehan Luo,Hami Gholamhosseini,Bin Han,Hexian Wang

Pharmacognosy Magazine,17(74):223-230
DOI: 10.4103/pm.pm_187_20
Published: July 12, 2021
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Costunolide (Co) attenuated the release of lactate dehydrogenase. #P < 0.05 versus control group, *P < 0.05 versus Oxygen‑glucose deprivation/reoxygenation group
Original Article

Costunolide attenuates oxygen-glucose deprivation/reoxygenation-induced apoptosis in mouse brain slice through inhibiting caspase expression

Huixia Ma,Yafei Zhu,Zhengjun Zhang,Xinhui Zhang,Qipeng Zhao

Pharmacognosy Magazine,17(74):231-235
DOI: 10.4103/pm.pm_360_20
Published: July 12, 2021
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Lipopolysaccharide induced nitric oxide production in RAW 264.7
Original Article

Identification of chemical constituents and inhibitory effect of Ficus deltoidea fraction against lipopolysaccharide-induced nuclear factor-kappa B inflammatory pathway in murine macrophage 264.7 cells

Rameshkumar Santhanam,Gothai Sivapragasam,Thiruventhan Karunakaran,Katyakyini Muniandy,Senthilkumar Palani Kandasamy,Arulselvan Palanisamy

Pharmacognosy Magazine,17(74):236-243
DOI: 10.4103/pm.pm_433_20
Published: July 12, 2021
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The cytotoxic effect of ferruginol on HCT-116 cells was measured by MTT assay
Original Article

Ferruginol-induced apoptosis in Human Colon Cancer Cells (HCT-116) through the mitochondria-mediated apoptotic pathway

Hua-Long Lin,Pei-Rui Chen,Chun-Chun Mao,Wei-E Zheng,Jia-Qi Wang

Pharmacognosy Magazine,17(74):244-249
DOI: 10.4103/pm.pm_53_20
Published: July 12, 2021
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Chemical structure of citral
Original Article

Citral promotes the cell proliferation, differentiation, and calcium mineralization in human osteoblast-like MG-63 cells

Hong Mu,Ying Pang,Lili Liu,Fengshan Li,Jianqi Wang

Pharmacognosy Magazine,17(74):250-255
DOI: 10.4103/pm.pm_242_20
Published: July 12, 2021
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Cellular protective effect of AOE and GAL on INDO-induced RGM-1 cellular injury. After 18 h treatment, AOE and GAL accelerated the INDO-damaged RGM-1 cell proliferation. ###P < 0.001 compared with the control group; **P < 0.01, ***P < 0.001 compared with the model group. AOE: The extract of Alpinia officinarum;
Original Article

The gastroprotective effect of alpinia officinarum extract on indomethacin-induced topical injuries in RGM-1 Cells: Involvement of H+/K+-ATPase- and mitochondrial-mediated apoptosis

Li Li,Jingwen Gong,Hailong Li,Mingyan Zhou,Yinfeng Tan,Junqing Zhang

Pharmacognosy Magazine,17(74):256-262
DOI: 10.4103/pm.pm_65_20
Published: July 12, 2021
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Structure of isolated novel marker compounds A and B from non-carbonyl Curcuma longa
Original Article

In silico studies on the therapeutic potential of novel marker compounds isolated from chemically modified bioactive fraction from Curcuma longa (Non-carbonyl Curcuma longa)

Arshi Naqvi,Reem A.K. Al-Harbi,Samah Ali,Richa Malasoni,Swati Gupta,Anil Kumar Dwivedi

Pharmacognosy Magazine,17(74):263-267
DOI: 10.4103/pm.pm_317_20
Published: July 12, 2021
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Original Article

Attenuation of kirenol inflammationinduced by ischemic/reperfusion cerebral infarction stroke via TLR4/ NLRP3 signaling pathway: An in vivo approach

Debo Yun,Yujiao Yang,Bin Shang,Heng Dong,Bo Luo,Tahani Awad Alahmadi,Qing Luo

Pharmacognosy Magazine,17(74):268-274
DOI: 10.4103/pm.pm_261_20
Published: July 12, 2021
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The effect of resveratrol on the pro‑inflammatory cytokines and inflammatory mediators in lipopolysaccharide‑induced RAW 264.7 cells. (a) Interleukin‑4, (b) interleukin‑10, (c) interleukin‑18, and (d) nuclear factor‑kappa B in culture supernatant and estimated via using the ELISA. All the values present as ± standard deviation of three or more replicates. ^^^P < 0.001 compared with control; * P < 0.05, **P < 0.01, and ***P < 0.001 compared with the lipopolysaccharide treated with alone, respectively
Original Article

Resveratrol exerts anti-inflammatory effect in lipopolysaccharide-induced lung inflammation via downregulation of antioxidant and inflammatory mediators

Xinxin Liang,Jian Shen,Xueming Duan,Rongbing Zhou,Peng Liu,Xiaoming CHi

Pharmacognosy Magazine,17(74):275-281
DOI: 10.4103/pm.pm_41_20
Published: July 12, 2021
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Effects of Ginsenoside Rb1 on Serum Brain Natriuretic Peptide Level and Caspase‑3 Protein Expression in Cardiomyocytes of Rats with Chronic Heart Failure
Original Article

Effects of ginsenoside Rb1 on serum brain natriuretic peptide level and caspase-3 protein expression in cardiomyocytes of rats with chronic heart failure

Yaoyao Wang,Yujiang Chen,Mao Yang,Chunlin Chen

Pharmacognosy Magazine,17(74):282-287
DOI: 10.4103/pm.pm_561_19
Published: July 12, 2021
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Effect of OIS on NO production. BV2 cells were incubated with OIS extract for 24 h, in the presence or absence of 1 μg/ml LPS, and NO production was assessed through the Griess reaction assay. Data are presented as the mean ± the standard error of the mean (n = 3). *P < 0.05 versus control group; #P < 0.05, ##P < 0.01 versus LPS‑treated group
Original Article

Oroxylum indicum Kurz (L.) seed extract exerts antioxidant and anti-inflammatory effects on lipopolysaccharide-stimulated BV2 microglial cells

Nootchanat Mairuae,Poonlarp Cheepsunthorn,Benjaporn Buranrat,Supataechasit Yannasithinon

Pharmacognosy Magazine,17(74):288-292
DOI: 10.4103/pm.pm_393_20
Published: July 12, 2021
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Metabolomics Study on the Therapeutic Mechanism of Schisandra chinensis Polysaccharides on Concanavalin A‑Induced Immunological Liver Injury in Mic
Original Article

Metabolomics Study on the Therapeutic Mechanism of Schisandra chinensis Polysaccharides on Concanavalin A‑Induced Immunological Liver Injury in Mice

Lihua Chen,Yingying Shan,Chunmei Wang,He Li,Jianguang Chen,Jinghui Sun

Pharmacognosy Magazine,17(74):293-301
DOI: 10.4103/pm.pm_255_20
Published: July 12, 2021
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Antitrypanosomal and Antileishmanial Effects of the Hydroalcoholic Extract of Croton cajucara Benth and its 19‑nor‑Clerodane Chromatographic Fractions
Original Article

Antitrypanosomal and antileishmanial effects of the hydroalcoholic extract of Croton cajucara benth and its 19-nor-clerodane chromatographic fractions

Gerson S. Lima,Gerzia C. Machado,Maria A.M. Maciel,Aurea Echevarria

Pharmacognosy Magazine,17(74):302-306
DOI: 10.4103/pm.pm_345_20
Published: July 12, 2021
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High‑performance liquid chromatography chromatogram of Carthami flos extract (a) and standard compounds (b: Rutin and c: Isoquercitrin) at a wavelength of 280 nm
Original Article

Carthami flos induces apoptosis by activating caspases and regulating mitogen-activated protein kinase and reactive oxygen species signaling pathways in AGS human gastric cancer cells

Song Ee Han,Min Ji Kwon,Jeong Nam Kim,Eun Yeong Lim,Yun Tai Kim,Byung Joo Kim

Pharmacognosy Magazine,17(74):307-314
DOI: 10.4103/pm.pm_127_20
Published: July 12, 2021
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The reactive oxygen species level of RSC‑96 cells stimulated by hydrogen peroxide was influenced using Elaeagnus angustifolia L.
Original Article

Protective effects of Elaeagnus angustifolia L. leaves against H2O2-induced oxidative damage in Rat Schwann Cells (RSC-96) through regulation of PI3K/Akt signaling pathway

Yun Sun,Hui Yao,Xin Zhang,Xiao-Xuan Yuan,Han-Lin Xu

Pharmacognosy Magazine,17(74):315-320
DOI: 10.4103/pm.pm_275_20
Published: July 12, 2021
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Effects of different concentrations of lipopolysaccharide and resveratrol on RAW264.7. (
Original Article

Resveratrol attenuates inflammation by regulating macrophage polarization via inhibition of toll-like receptor 4/MyD88 signaling pathway

Dong-yan Li,Yu-Lin Cui,Hong Li,Si-Lin Huang,Yue Fan

Pharmacognosy Magazine,17(74):321-326
DOI: 10.4103/pm.pm_312_20
Published: July 12, 2021
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Immobility time of forced swimming test. After 3 weeks of treatments, the immobility time of rats during forced swimming was tested.
Original Article

Paeoniflorin prevents depression like behavior in rats by suppressing mitophagy mediated nod like receptor protein 3 inflammasome signaling

Meng Wang,Shuguang Yan,Jingyi Kong,Yongxue Zhou,Pei Xie

Pharmacognosy Magazine,17(74):327-333
DOI: 10.4103/pm.pm_85_20
Published: July 12, 2021
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Structure of lappaconitine hydrochloride
Original Article

Lappaconitine hydrochloride induces apoptosis and S phase cell cycle arrest through MAPK signaling pathway in human liver cancer HepG2 cells

Na Song,Junyi Ma,Xuemei Zhang,Danni Qu,Ling Hui,Chunyan Sang,Haining Li

Pharmacognosy Magazine,17(74):334-341
DOI: 10.4103/pm.pm_251_20
Published: July 12, 2021
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The selected six purple plants in the experiment
Original Article

Content determination of functional composition and antioxidant activity from six purple plants

Fang-Rong Cheng,Hong-Xin Cui,Ji-Li Fang,Ke Yuan,Song-Heng Jin,Xiang-Tao Zhu,Yong Xu

Pharmacognosy Magazine,17(74):342-347
DOI: 10.4103/pm.pm_203_20
Published: July 12, 2021
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Sample preparation parameters for the Heracles Ⅱ E‑nose analysis
Original Article

An analytic hierarchy process multi-criteria quantitative evaluation model of cinnamon decoction pieces

Zi-Ye Yang,Xin-Jie Wang,Yao Zhang,Hui Gao,Hui-Nan Wang,Gui-Mei Zhang,Pei-Hua Wang,Yue-Xin Cui,Meng-Yu Chen,Zhan Chen,Ying-Zi Wang

Pharmacognosy Magazine,17(74):348-354
DOI: 10.4103/pm.pm_306_20
Published: July 12, 2021
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Chemical Composition, Antimycobacterial and Antiinflammatory Activities of Iridoids and Triterpene from Psychotria suterella (Rubiaceae)
Original Article

Chemical composition, antimycobacterial and anti-inflammatory activities of iridoids and triterpene from Psychotria suterella (Rubiaceae)

Almir Ribeiro De Junior,Rafaela Oliveira Ferreira,Michel de Souza Passos,Milena Gonçalves Vieira,Lorena de Lima Gl Virgens,Sanderson Dias Calixto,Thatiana Lopes Biá Ventura,Elena Lassounskaia,Mario Geraldo de Carvalho,Raimundo Braz-Filho,Ivo José Curc Vieira

Pharmacognosy Magazine,17(74):355-359
DOI: 10.4103/pm.pm_93_20
Published: July 12, 2021
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Effect of crocetin on the DNA fragmentation and CYP2E1 of control and experimental rats
Original Article

Chemoprotective effect of crocetin against 1,2 dimethyl hydrazine induced colorectal cancer in albino wistar rats through antioxidant pathway

Peng Shao,Xiujuan Li,Xin Guan

Pharmacognosy Magazine,17(74):360-366
DOI: 10.4103/pm.pm_311_20
Published: July 12, 2021
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Schematic representation of cell cycle distribution in cells treated with brucine for 48 h.
Original Article

Isolation and anticancer effect of brucine in human colon adenocarcinoma cells HT-29

Zhenyu Feng,Shuang Meng,Xiaorong Zhou,Xiaojuan Ma,Zhengbao Zhao,Jianping Zhao

Pharmacognosy Magazine,17(74):367-372
DOI: 10.4103/pm.pm_95_20
Published: July 12, 2021
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Flow diagram of studies selection
Original Article

Efficacy and safety on Moringa oleifera on blood glucose and lipid profile: A meta-analysis

Wiraphol Phimarn,Bunleu Sungthong,Kittisak Wichaiyo

Pharmacognosy Magazine,17(74):373-378
DOI: 10.4103/pm.pm_49_20
Published: July 12, 2021
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Showed the effect of astragaloside IV on the lung weight ratio of LPS induced lung inflammation in standard deviation rats
Original Article

Potential effect of astragaloside IV on the lipopolysaccharide induced inflammation via the inactivation of NF-κB signaling pathway

Xuebo Yan,Tong Wang,Lei Fang,Jiong Wang

Pharmacognosy Magazine,17(74):379-386
DOI: 10.4103/pm.pm_267_20
Published: July 12, 2021
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IC50 of the Colocasia esculenta L. Schott corm mucilage on COX- 1, COX-2 and 5-LOX activity in acetic acid-induced rat colitis comparing to reference drugs
Original Article

Colocasia esculenta L. schott corm mucilage: A selective COX-2 inhibitor for treatment of irritable bowel syndrome

Nebal D. Eltanbouly,Samia M. Abdelwahab,Azza Ramy Abdel Monem,Samar M. Mouneir,Nesrin M. Fayek

Pharmacognosy Magazine,17(74):387-390
DOI: 10.4103/pm.pm_488_20
Published: July 12, 2021
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Effects of asiaticoside on the interleukin‑6, interleukin‑1β, interleukin‑10, and tumor necrosis factor‑alpha in the Freund’s complete adjuvant‑induced rheumatoid arthritis in rats.
Original Article

Antiarthritic activity of asiaticoside against the Freund's complete adjuvant-induced rheumatoid arthritis in experimental wistar rats

Xiaohui Zhou,Jiasong Zhao,Zheng Zhang,Chunmei Geng,Jinwei Ying

Pharmacognosy Magazine,17(74):391-398
DOI: 10.4103/pm.pm_247_19
Published: July 12, 2021
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