Naringenin reduced migration in osteosarcoma cells through downregulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 and snail

Yuh-Ming Chang¹, Ming-Cheng Lin², Ling-Zong Hong³, Pei-Ni Chen⁴, Yu-Hsin Tsai⁴, You-Cheng Hseu⁵, Ke-Min Chen⁶, Li-Sung Hsu⁷, Ting-Hsien Kao^8
1 Department of Neurology, Division of Internal Medicine, Hsinchu Mackay Memorial Hospital, Hsinchu; Institute of Biochemistry, Microbiology, and Immunology, Chung Shan Medical University, Taichung, Taiwan
² Department of Internal Medicinel; School of Medicine, Chung Shan Medical University, Taichung, Taiwan
³ Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan
⁴ Institute of Biochemistry, Microbiology, and Immunology, Chung Shan Medical University, Taichung, Taiwan
⁵ Department of Cosmeceutics, College of Biopharmaceutical and Food Sciences, China Medical University; Department of Health and Nutrition Biotechnology, Asia University; Chinese Medicine Research Center, China Medical University, Taichung, Taiwan
⁶ Department of Parasitology, School of Medicine, Chung Shan Medical University, Taichung, Taiwan
⁷ Institute of Biochemistry, Microbiology, and Immunology; Clinical Laboratory, Chung Shan Medical University Hospital, Taichung, Taiwan
⁸ Division of Functional Neurosurgery, Neurological Institute, Taichung Veterans General Hospital, Taichung; Department of Neurosurgery, Lin Shin Medical Corporation Lin Shin Hospital, Taichung, Taiwan