In-vitro Anticancer Activity of Standard Extracts Used in Ayurveda

SN Gaidhani; GS Lavekar; AS Juvekar; S Sen; Arjun Singh; Suman Kumari

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Abstract

Pharmacognosy Magazine,2009,5,20s,425-429.

Published:February 2010

Type:Research Article

Authors:

Author(s) affiliations:

SN Gaidhani¹^*, GS Lavekar¹, AS Juvekar², S Sen², Arjun Singh¹, Suman Kumari¹
¹Central Council For Research in Ayurveda & Siddha, Dept. of Ayush, Ministry of Health & F.W., Janakpuri, New Delhi-58, India
²ACTREC, TMC Kharghar, Navi Mumbai, India

Abstract:

The hydro-alcoholic extracts of five Ayurvedic medicinal plants, pericarp of Terminalia chebula, rhizome of Acorus calamus, stem bark of Bauhinia variegate, whole plant of Phyllanthus amarus, root of Glycyrrhiza glabra were evaluated for their antiproliferative activity on fourteen cancer cell lines. These plant extracts were tested by sulforhodamine-B (SRB) assay for its anti proliferative activity and four extracts except Glycyrrhiza glabra were found active against prostrate cancer cell line (DU145. In addition to this Terminalia chebula exhibited activity against leukemia cancer cell line (K562).

Keywords:Anticancer, Cell Line, SRB Assay, standardization

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Vancouver Style
Gaidhani SN, Lavekar GS, Juvekar AS, Sen S, Singh A, Kumari S. In-vitro Anticancer Activity of Standard Extracts Used in Ayurveda. Pharmacognosy Magazine [Internet]. 2009;5(20s):425-429. http://www.phcog.com/text.asp?2009/5/20/425/59769