A pentacyclic triterpenoid possessing anti-inflammatory activity from the fruits of Dregea volubilis

The aim of the study is to find anti-inflammatory activity of the compound obtained from the petroleum ether extract of the fruits of Dregea volubilis. Fruits of Dregea volubilis were extracted by petroleum ether and through column chromatography led to obtain a compound. The structure of the compound was determined on the basis of IR, MASS, NMR (PMR, CMR and DEPT) spectroscopic analysis. The compound was screened for anti-inflammatory activity in albino rats using acute carageenan induced paw oedema. The petroleum ether extract of the fruits of Dregea volubilis Benth led to isolation and characterization of a pentacyclic triterpenoid compound designated as taraxerol and characterized as D- friedoolean- 14- en, 3 ol [Figure 1]. It has shown significant anti-inflammatory activity in albino rats. Anti-inflammatory activity in albino rats has been shown by taraxerol obtained from the petroleum ether extract of the fruits of Dregea volubilis.