Close
  Indian J Med Microbiol
 

Figure 3: Effects of bisacurone on the histopathology of femur bone after fracture in female OVX-induced OP rats. Representative histological images from (a) sham; (b) control; (c) Alendronate (3 mg/kg); (d) Bisacurone (50 μg/kg); (e) Bisacurone (100 μg/kg) and (f) Alendronate + bisacurone (3 mg/kg and 100 μg/kg)-treated rats. Images stained with H and E (×100). The quantitative representation of histological score (g). Data were expressed as mean ± S.E.M. (n = 3), and one-way ANOVA followed by the Kruskal–Wallis test was applied for post hoc analysis. For comparison with control group: *P < 0.05, comparison with sham group: #P < 0.05 and comparison with one another: $P < 0.05. Sham: Sham-operated rats; Control: OVX control rats; a (3): Alendronate (3 mg/kg, s.c.)-treated rats; b (25): Bisacurone (25 μg/kg, p.o.)-treated rats; b (50): Bisacurone (50 μg/kg, p.o.)-treated rats; b (100): Bisacurone (100 μg/kg, p.o.)-treated rats; A (3) + B (100): Alendronate (3 mg/kg, s.c.) and Bisacurone (100 μg/kg, p.o.)-treated rats

Figure 3: Effects of bisacurone on the histopathology of femur bone after fracture in female OVX-induced OP rats. Representative histological images from (a) sham; (b) control; (c) Alendronate (3 mg/kg); (d) Bisacurone (50 μg/kg); (e) Bisacurone (100 μg/kg) and (f) Alendronate + bisacurone (3 mg/kg and 100 μg/kg)-treated rats. Images stained with H and E (×100). The quantitative representation of histological score (g). Data were expressed as mean ± S.E.M. (<i>n</i> = 3), and one-way ANOVA followed by the Kruskal–Wallis test was applied for <i>post hoc</i> analysis. For comparison with control group: *<i>P</i> < 0.05, comparison with sham group: <sup>#</sup><i>P</i> < 0.05 and comparison with one another: <sup>$</sup><i>P</i> < 0.05. Sham: Sham-operated rats; Control: OVX control rats; a (3): Alendronate (3 mg/kg, s.c.)-treated rats; b (25): Bisacurone (25 μg/kg, p.o.)-treated rats; b (50): Bisacurone (50 μg/kg, p.o.)-treated rats; b (100): Bisacurone (100 μg/kg, p.o.)-treated rats; A (3) + B (100): Alendronate (3 mg/kg, s.c.) and Bisacurone (100 μg/kg, p.o.)-treated rats