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  Indian J Med Microbiol
 

Figure 1: Effects of bisacurone on pain-related behaviors after fracture in female OVX-induced OP rats. (a) Spontaneous guarding; (b) Spontaneous flinching; (c) Hind limb weight-bearing capacity in rats. Data are expressed as mean ± S.E.M. (n = 6) and analyzed by one-way ANOVA followed by the Bonferroni test. *P < 0.05 as compared to the control group, #P < 0.05 as compared to the sham group, $P < 0.05 as compared to one another. Sham: Sham-operated rats; Control: OVX control rats; a (3): Alendronate (3 mg/kg, s.c.)-treated rats; B (25): Bisacurone (25 μg/kg, p.o.)-treated rats; b (50): Bisacurone (50 μg/kg, p.o.)-treated rats; B (100): Bisacurone (100 μg/kg, p.o.)-treated rats; a (3) + b (100): Alendronate (3 mg/kg, s.c.) and Bisacurone (100 μg/kg, p.o.)-treated rats

Figure 1: Effects of bisacurone on pain-related behaviors after fracture in female OVX-induced OP rats. (a) Spontaneous guarding; (b) Spontaneous flinching; (c) Hind limb weight-bearing capacity in rats. Data are expressed as mean ± S.E.M. (n = 6) and analyzed by one-way ANOVA followed by the Bonferroni test. *<i>P</i> < 0.05 as compared to the control group, #<i>P</i> < 0.05 as compared to the sham group, $<i>P</i> < 0.05 as compared to one another. Sham: Sham-operated rats; Control: OVX control rats; a (3): Alendronate (3 mg/kg, s.c.)-treated rats; B (25): Bisacurone (25 μg/kg, p.o.)-treated rats; b (50): Bisacurone (50 μg/kg, p.o.)-treated rats; B (100): Bisacurone (100 μg/kg, p.o.)-treated rats; a (3) + b (100): Alendronate (3 mg/kg, s.c.) and Bisacurone (100 μg/kg, p.o.)-treated rats