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  Indian J Med Microbiol
 

Figure 1: Experimental design representing conditioned fear + single prolonged stress–induced PTSD model in Swiss albino mice for evaluation of efficacy of TnCE treatment evaluated through (a) social behavior test, (b) contextual fear conditioning, (c) forced swim test, (d) open field test and (e) elevated plus maze. The 6 experimental groups used in this study has also been depicted (n = 8). AS (c): Auditory stimulus (as conditioned stimulus), EFS (u): Electric foot shock (as unconditioned stimulus (1 mA), CF: Conditioned fear; SPS: Single prolonged stress (restrain + forced swim test + predator betting scent + diethyl ether inhalation), TnCE: Tinospora cordifolia (ethanolic extract); SeR: Sertraline

Figure 1: Experimental design representing conditioned fear + single prolonged stress–induced PTSD model in Swiss albino mice for evaluation of efficacy of TnCE treatment evaluated through (a) social behavior test, (b) contextual fear conditioning, (c) forced swim test, (d) open field test and (e) elevated plus maze. The 6 experimental groups used in this study has also been depicted (<i>n</i> = 8). AS (c): Auditory stimulus (as conditioned stimulus), EFS (u): Electric foot shock (as unconditioned stimulus (1 mA), CF: Conditioned fear; SPS: Single prolonged stress (restrain + forced swim test + predator betting scent + diethyl ether inhalation), TnCE: <i>Tinospora cordifolia</i> (ethanolic extract); SeR: Sertraline