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  Indian J Med Microbiol
 

Figure 2: Effects of CBTM-E375 on LPS-induced TNF-α, IL-6, and IL-8 levels in HUVECs. HUVECs were pretreated for 12 h with the indicated concentrations of CBTM-E375 and stimulated for 24 h with LPS (1 μg/mL). The concentration of IL-6, IL-8, and TNF-α (a-c) were determined as described under materials and methods. Data represent mean values of 3 experiments ± standard deviation. #P < 0.05 versus control group; ##P < 0.01 versus control group; *P < 0.05 versus LPS group; **P < 0.01 versus LPS group; was considered to be statistically significant. HUVECs: Human umbilical vein endothelial cells; TNF-α: Tumour necrosis factor-α; IL-8: Interleukin-8; IL-6: Interleukin-6

Figure 2: Effects of CBTM-E375 on LPS-induced TNF-α, IL-6, and IL-8 levels in HUVECs. HUVECs were pretreated for 12 h with the indicated concentrations of CBTM-E375 and stimulated for 24 h with LPS (1 μg/mL). The concentration of IL-6, IL-8, and TNF-α (a-c) were determined as described under materials and methods. Data represent mean values of 3 experiments ± standard deviation. <sup>#</sup><i>P</i> < 0.05 versus control group; <sup>##</sup><i>P</i> < 0.01 versus control group; *<i>P</i> < 0.05 versus LPS group; **<i>P</i> < 0.01 versus LPS group; was considered to be statistically significant. HUVECs: Human umbilical vein endothelial cells; TNF-α: Tumour necrosis factor-α; IL-8: Interleukin-8; IL-6: Interleukin-6