Close
  Indian J Med Microbiol
 

Figure 2: (a) Hierarchical clustering analysis of differentially expressed genes. The hierarchical cluster image shows the differential gene expression profiles in DRUG and NC groups. The heat maps display a color scale: red indicates upregulation, whereas green represents downregulation. The columns and rows in the heat maps represent samples and differentially expressed genes, respectively. Color brightness represents the degree of difference, as shown in the color bar. (b) Difference significance analysis of differentially expressed genes. The volcano plot shows the distribution of differentially expressed genes in grouping comparison and fold change on x-axis. The P value on y-axis represents the significance of the difference. Green lines represent the threshold value of P and multiple screening, respectively. Each point in the diagram is a detected gene probe. Red dots represent the difference probes above each group.,Fold change,>3 and false discovery rate <0.05. The significance of gene differential expression between experimental and control groups is indicated. (c) Principal component analysis of differentially expressed genes. The red dots represent the DRUG samples and the green dots represent the NC sample. The different experimental groups are separated from one another, the experimental data show good repeatability, thereby showing good specificity

Figure 2: (a) Hierarchical clustering analysis of differentially expressed genes. The hierarchical cluster image shows the differential gene expression profiles in DRUG and NC groups. The heat maps display a color scale: red indicates upregulation, whereas green represents downregulation. The columns and rows in the heat maps represent samples and differentially expressed genes, respectively. Color brightness represents the degree of difference, as shown in the color bar. (b) Difference significance analysis of differentially expressed genes. The volcano plot shows the distribution of differentially expressed genes in grouping comparison and fold change on x-axis. The <i>P</i> value on y-axis represents the significance of the difference. Green lines represent the threshold value of <i>P</i> and multiple screening, respectively. Each point in the diagram is a detected gene probe. Red dots represent the difference probes above each group.,Fold change,>3 and false discovery rate <0.05. The significance of gene differential expression between experimental and control groups is indicated. (c) Principal component analysis of differentially expressed genes. The red dots represent the DRUG samples and the green dots represent the NC sample. The different experimental groups are separated from one another, the experimental data show good repeatability, thereby showing good specificity