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Figure 4: The neuroprotective effects of compound 6 (a) and compound 9 (b) on glutameate-induced cytotoxicity in HT22 cells. Cell was pretreated with 0.1, 1, and 10 μM of compound 6 and 10, 50, and 100 μM of compound 9 and trolox (30 μM). Then 30 μl of 2.5 mM glutamate was treated after 1 h. Each bar represents the mean ± standard deviation of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 versus glutamate-injured cells (ANOVA) |
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