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  Indian J Med Microbiol
 

Figure 6: Effects of phloretin on renal histology of experimental rats. Control rats show the normal architecture whereas cisplatin-induced kidney damage. The treatment with the high-dose of phloretin (50 mg/kg) was demonstrated the increased attenuation effects than the low-dose treatment of phloretin (25 mg/kg). The standard drug silymarin (50 mg/kg) also showed the protective effects against the cisplatin-induced renal cellular damage and tissue necrosis in experimental rats

Figure 6: Effects of phloretin on renal histology of experimental rats. Control rats show the normal architecture whereas cisplatin-induced kidney damage. The treatment with the high-dose of phloretin (50 mg/kg) was demonstrated the increased attenuation effects than the low-dose treatment of phloretin (25 mg/kg). The standard drug silymarin (50 mg/kg) also showed the protective effects against the cisplatin-induced renal cellular damage and tissue necrosis in experimental rats