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  Indian J Med Microbiol
 

Figure 4: Inhibitory effect of mahanimbine against neuroinflammatory markers in lipopolysaccharides-induced mice. (a-d) Cytokine levels were determined using the multiplex assay kit. (e) Cyclooxygenase activity in the brain was measured using ELISA kit. (f) Cyclooxygenase-2 gene expression was validated using real-time-polymerase chain reaction. Each bar represents mean ± standard error means (n = 6). *P < 0.05 and ***P < 0.001 versus control group; #P < 0.05, ##P < 0.01, and ###P < 0.001 versus lipopolysaccharides-induced group

Figure 4: Inhibitory effect of mahanimbine against neuroinflammatory markers in lipopolysaccharides-induced mice. (a-d) Cytokine levels were determined using the multiplex assay kit. (e) Cyclooxygenase activity in the brain was measured using ELISA kit. (f) Cyclooxygenase-2 gene expression was validated using real-time-polymerase chain reaction. Each bar represents mean ± standard error means (<i>n</i> = 6). *<i>P</i> < 0.05 and ***<i>P</i> < 0.001 versus control group; <sup>#</sup><i>P</i> < 0.05, <sup>##</sup><i>P</i> < 0.01, and <sup>###</sup><i>P</i> < 0.001 versus lipopolysaccharides-induced group