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  Indian J Med Microbiol
 

Figure 1: HC9 retarded growth of subcutaneous melanoma tumors in C57BL/6 mice. (a) Scheme showing tumor generation and drug intervention in mice. B16F1 cells were subcutaneously injected at a density of 5 × 105 cells/animal. The palpable tumors were observed on the 8th day. Doxorubicin was given on the 1st, 5th, and 9th days once tumors had developed. HC9 was given from day 1 up to 2 weeks. (b) Representative photographs of tumors from tumor control, doxorubicin, and HC9-treated mice. (c) Graph representing a decrease in tumor volume after HC9 treatment. Data have been represented as mean ± standard deviation. The experiment was done twice (n = 4 mice/group). The values with *P < 0.05 were considered to be statistically significant

Figure 1: HC9 retarded growth of subcutaneous melanoma tumors in C57BL/6 mice. (a) Scheme showing tumor generation and drug intervention in mice. B16F1 cells were subcutaneously injected at a density of 5 × 105 cells/animal. The palpable tumors were observed on the 8<sup>th</sup> day. Doxorubicin was given on the 1<sup>st</sup>, 5<sup>th</sup>, and 9<sup>th</sup> days once tumors had developed. HC9 was given from day 1 up to 2 weeks. (b) Representative photographs of tumors from tumor control, doxorubicin, and HC9-treated mice. (c) Graph representing a decrease in tumor volume after HC9 treatment. Data have been represented as mean ± standard deviation. The experiment was done twice (<i>n</i> = 4 mice/group). The values with *<i>P</i> < 0.05 were considered to be statistically significant