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  Indian J Med Microbiol
 

Figure 5: The effects of EE on the apoptosis and proliferation of LCC cells in vivo. (a) Flow cytometry analyses of apoptosis in LCC cells of tumor-bearing mice. (b) The G0/G1 proportions of LCC cells in tumor-bearing mice treated with EE are presented. (c) The immunochemistry detections of PCNA between groups. (d) The mRNA expression levels of caspase-9, Bax, and Bcl-2 were analyzed by quantitative real-time PCR in tumor tissues. The group without EE treatment was a control. Data are expressed as the mean ± SD *P < 0.05 versus control. SOD: Superoxide dismutase; CAT: Catalase; GSH-Px: Glutathione peroxidase; SD: Standard deviation; LCC: Large cell carcinoma; EE: Euphorbiaceae extract; PCNA: Proliferating cell nuclear antigen; PCR: polymerase chain reaction

Figure 5: The effects of EE on the apoptosis and proliferation of LCC cells <i>in vivo</i>. (a) Flow cytometry analyses of apoptosis in LCC cells of tumor-bearing mice. (b) The G0/G1 proportions of LCC cells in tumor-bearing mice treated with EE are presented. (c) The immunochemistry detections of PCNA between groups. (d) The mRNA expression levels of caspase-9, Bax, and Bcl-2 were analyzed by quantitative real-time PCR in tumor tissues. The group without EE treatment was a control. Data are expressed as the mean ± SD *<i>P</i> < 0.05 versus control. SOD: Superoxide dismutase; CAT: Catalase; GSH-Px: Glutathione peroxidase; SD: Standard deviation; LCC: Large cell carcinoma; EE: <i>Euphorbiaceae</i> extract; PCNA: Proliferating cell nuclear antigen; PCR: polymerase chain reaction