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Figure 5: Effects of Lysiphyllum strychnifolium on the plasma uric acid concentration on potassium oxonate-induced hyperuricemic mice (a) and rate of uric acid production in homogenated mice livers (b). Group 1 represents normal control group; Group 2 means untreated-potassium oxonate induced hyperuricemic mice; Group 3 represents potassium oxonate-induced hyperuricemic mice treated with allopurinol (5 mg/kg); groups 4 and 5 represent potassium oxonate-induced hyperuricemic mice treated with 100 and 200 mg/kg of Lysiphyllum strychnifolium, respectively. Data are expressed as mean ± standard error of the mean (n = 6–8). ##represents P < 0.01, compared to normal control mice, respectively, compared to normal control mice. * and ** represent P < 0.05 and P < 0.01 respectively, compared to untreated potassium oxonate-induced hyperuricemic mice |
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