Close
  Indian J Med Microbiol
 

Figure 8: Effect of HEZA pretreatment on LPS-induced changes in brain (a) NFκB; B, (b) Nrf2, and (c) Caspase-3 mRNA expression in the hippocampus of mice. GAPDH was used as positive control to assess the equal loading of sample. Values are expressed as mean ± standard error of the mean; (n = 6). #P < 0.05; ###P < 0.001 compared with vehicle control. *P < 0.05; **P < 0.01; ***P < 0.001 compared with LPS-challenged group. NFκB: Nuclear factor-κB; Nrf2: Nuclear factor (erythroid-derived 2)-like 2; LPS: Lipopolysaccharide; HEZA: Hydroethanolic extract of Zanthoxylum alatum seeds

Figure 8: Effect of HEZA pretreatment on LPS-induced changes in brain (a) NFκB; B, (b) <i>Nrf2</i>, and (c) <i>Caspase-3</i> mRNA expression in the hippocampus of mice. GAPDH was used as positive control to assess the equal loading of sample. Values are expressed as mean ± standard error of the mean; (<i>n</i> = 6). <sup>#</sup><i>P</i> < 0.05; <sup>###</sup><i>P</i> < 0.001 compared with vehicle control. *<i>P</i> < 0.05; **<i>P</i> < 0.01; ***<i>P</i> < 0.001 compared with LPS-challenged group. NFκB: Nuclear factor-κB; Nrf2: Nuclear factor (erythroid-derived 2)-like 2; LPS: Lipopolysaccharide; HEZA: Hydroethanolic extract of <i>Zanthoxylum alatum</i> seeds