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  Indian J Med Microbiol
 

Figure 6: Representative images showing immunohistochemical staining of nuclear factor-like 2 expression in the myocardium. (a) Vehicle control, (b) isoproterenol treated, (c) icariin per se, (d) sildenafil per se, (e) icariin 1+ isoproterenol, (f) icariin 5+ isoproterenol, (g) icariin 10+ isoproterenol, (h) sildenafil + isoproterenol. Bar graph showing the level of nuclear factor-like 2 activation in myocardium expressed as the optical density. Values are expressed as mean ± standard error of mean (n = 6), where ***P < 0.001 versus normal control; ##P < 0.01, and ###P < 0.001 versus isoproterenol treated

Figure 6: Representative images showing immunohistochemical staining of nuclear factor-like 2 expression in the myocardium. (a) Vehicle control, (b) isoproterenol treated, (c) icariin <i>per se</i>, (d) sildenafil <i>per se</i>, (e) icariin 1+ isoproterenol, (f) icariin 5+ isoproterenol, (g) icariin 10+ isoproterenol, (h) sildenafil + isoproterenol. Bar graph showing the level of nuclear factor-like 2 activation in myocardium expressed as the optical density. Values are expressed as mean ± standard error of mean (<i>n</i> = 6), where ***<i>P</i> < 0.001 versus normal control; <sup>##</sup><i>P</i> < 0.01, and <sup>###</sup><i>P</i> < 0.001 versus isoproterenol treated