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  Indian J Med Microbiol
 

Figure 2: The messenger ribonucleic acid expression of hepatic CYP1A2 and CYP2B1/2 in male Sprague Dawley rats treated with Guibi-tang. (a) Male rats were treated orally with Guibi-tang (1000, 2000, or 5000 mg/kg/day) or vehicle once a day for 13 weeks. The messenger ribonucleic acid expression of CYP1A2 and 2B1/2 was analyzed by reverse transcription-polymerase chain reaction. The messenger ribonucleic acid levels of hepatic CYP1A2 (b) and CYP2B1/2 (c) were normalized to that of glyceraldehyde-3-phosphate dehydrogenase. Values are expressed as mean ± standard error of the mean (n = 8). **P < 0.01 versus vehicle control group

Figure 2: The messenger ribonucleic acid expression of hepatic CYP1A2 and CYP2B1/2 in male Sprague Dawley rats treated with <i>Guibi-tang</i>. (a) Male rats were treated orally with <i>Guibi-tang</i> (1000, 2000, or 5000 mg/kg/day) or vehicle once a day for 13 weeks. The messenger ribonucleic acid expression of CYP1A2 and 2B1/2 was analyzed by reverse transcription-polymerase chain reaction. The messenger ribonucleic acid levels of hepatic CYP1A2 (b) and CYP2B1/2 (c) were normalized to that of glyceraldehyde-3-phosphate dehydrogenase. Values are expressed as mean ± standard error of the mean (<i>n</i> = 8). **<i>P</i> < 0.01 versus vehicle control group