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  Indian J Med Microbiol
 

Figure 4: Effect of TAX on protein expression of AhR, CYP1A1, and CYP1B1. Western blot analysis of AhR (B), CYP1A1 and CYP1B1 (A) expression in cytoplasmic fraction of the DMBA-induced mammary cell extracts with or without TAX; the relative phosphorylation levels normalized with the ß-actin and converted to fold induction above the control value as shown in adjacent bar diagrams. Each column represents the mean standard error of the mean (n = 3); ***P < 0.001; **P < 0.01; *P < 0.05 as compared to control. Group I - Control; Group II - DMBA (20 mg); Group III - DMBA (20 mg) + TAX (10 mg/kg b. w.); Group IV - DMBA (20 mg) + TAX (20 mg/kg b. w.); Group V - DMBA (20 mg) + TAX (40 mg/kg b. w.). TAX: Taxifolin, DMBA: 7,12-dimethylbenz(a)anthracene

Figure 4: Effect of TAX on protein expression of AhR, CYP1A1, and CYP1B1. Western blot analysis of AhR (B), CYP1A1 and CYP1B1 (A) expression in cytoplasmic fraction of the DMBA-induced mammary cell extracts with or without TAX; the relative phosphorylation levels normalized with the ß-actin and converted to fold induction above the control value as shown in adjacent bar diagrams. Each column represents the mean standard error of the mean (<i>n</i> = 3); ***<i>P</i> < 0.001; **<i>P</i> < 0.01; *<i>P</i> < 0.05 as compared to control. Group I - Control; Group II - DMBA (20 mg); Group III - DMBA (20 mg) + TAX (10 mg/kg b. w.); Group IV - DMBA (20 mg) + TAX (20 mg/kg b. w.); Group V - DMBA (20 mg) + TAX (40 mg/kg b. w.). TAX: Taxifolin, DMBA: 7,12-dimethylbenz(a)anthracene