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  Indian J Med Microbiol
 

Figure 5: Effects of cyasterone and chikusetsusaponin IV on the levels of malondialdehyde (a), superoxide dismutase (b), cyclooxygenase-2 (c), endothelial nitric oxide synthase (d), thromboxane 2 (e), and endothelin (f) with cyasterone, chikusetsusaponin IV (50, 100, and 200 mM) for 24 h, and then stimulated without or with thrombin (15 U/mL) for 24 h. Aspirin (100 mM) was taken as a positive control. Results are expressed as mean ± standard deviation of six independent experiments. ###P < 0.001 versus blank group; *P < 0.05, **P < 0.01, ***P < 0.001 versus Model group. aP < 0.05, aaP < 0.01, aaaP < 0.001 as compared with aspirin group

Figure 5: Effects of cyasterone and chikusetsusaponin IV on the levels of malondialdehyde (a), superoxide dismutase (b), cyclooxygenase-2 (c), endothelial nitric oxide synthase (d), thromboxane 2 (e), and endothelin (f) with cyasterone, chikusetsusaponin IV (50, 100, and 200 mM) for 24 h, and then stimulated without or with thrombin (15 U/mL) for 24 h. Aspirin (100 mM) was taken as a positive control. Results are expressed as mean ± standard deviation of six independent experiments. <sup>###</sup><i>P</i> < 0.001 versus blank group; *<i>P</i> < 0.05, **<i>P</i> < 0.01, ***<i>P</i> < 0.001 versus Model group. <sup>a</sup><i>P</i> < 0.05, <sup>aa</sup><i>P</i> < 0.01, <sup>aaa</sup><i>P</i> < 0.001 as compared with aspirin group