Close
  Indian J Med Microbiol
 

Figure 6: Effect of F4d1, F4c4, and F4c5 subfractions purified from F4 fraction of Nigella sativa hexane extract on caspase-3 and -9 activity. Cell pretreated with subfractions 24 h before exposure to MPP+. Caspase-3 and -9 activity was measured by colorimetric detection of p-nitroaniline and expressed as percent of control. Data are expressed as the mean ± standard error of the mean of three separate experiments. ##P < 0.01 versus control *P < 0.01 versus MPP+ treated cells. MPP+: 1-methyl-4-phenylpyridinium. *P<0.05, **P<0.01 versus MPP+ treated cells

Figure 6: Effect of F4d1, F4c4, and F4c5 subfractions purified from F4 fraction of <i>Nigella sativa</i> hexane extract on caspase-3 and -9 activity. Cell pretreated with subfractions 24 h before exposure to MPP<sup>+</sup>. Caspase-3 and -9 activity was measured by colorimetric detection of p-nitroaniline and expressed as percent of control. Data are expressed as the mean ± standard error of the mean of three separate experiments. <sup>##</sup><i>P</i> < 0.01 versus control *<i>P</i> < 0.01 versus MPP<sup>+</sup> treated cells. MPP<sup>+</sup>: 1-methyl-4-phenylpyridinium. *<i>P</i><0.05, **<i>P</i><0.01 versus MPP<sup>+</sup> treated cells