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Figure 6: FIC50 and FIC90 based isobolograms (graphs 1&2 respectively) of embelin mixtures with CQ when they were combined at ratios of 7:3, 5:5 and 3:7 (CQ/embelin). They were used at a concentration equivalent to 16XIC50 of the drug against B hematin formation. The straight line represents line of additivity while the broken line represents the FIC50 and FIC90 based isobologram curves. |
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