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  Indian J Med Microbiol
 

Figure 3: Effects of muscarinic receptor subtype antagonists on daikenchuto-induced pacemaker potential depolarization in cultured interstitial cells of Cajal from mouse small intestine. Pacemaker potentials were depolarized when interstitial cells of Cajal were exposed to daikenchuto (10 mg/ml) in the presence of methoctramine (a muscarinic M2 receptor antagonist; 10 μM) (a)in the presence of 4-DAMP (a muscarinic M3 receptor antagonist; 10 μM) (b). Responses to daikenchuto in the presence of different receptor antagonists (c). Bars represent mean ± standard error of the means. **P < 0.01. Significantly different from non-treated controls. CTRL: ControlMethoct: Methoctramine

Figure 3: Effects of muscarinic receptor subtype antagonists on daikenchuto-induced pacemaker potential depolarization in cultured interstitial cells of Cajal from mouse small intestine. Pacemaker potentials were depolarized when interstitial cells of Cajal were exposed to daikenchuto (10 mg/ml) in the presence of methoctramine (a muscarinic M2 receptor antagonist; 10 μM) (a)in the presence of 4-DAMP (a muscarinic M3 receptor antagonist; 10 μM) (b). Responses to daikenchuto in the presence of different receptor antagonists (c). Bars represent mean ± standard error of the means. **<i>P</i> < 0.01. Significantly different from non-treated controls. CTRL: ControlMethoct: Methoctramine