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  Indian J Med Microbiol
 

Figure 3: Effect of thymoquinone on intestinal tumor necrosis factor-alpha in methotrexate-induced intestinal toxicity in rats. Animal groups tested are control group, animals treated with thymoquinone alone, animals treated with methotrexate alone, or with methotrexate together with thymoquinone pre-treatment. Values are representation of 8 observations as means ± SEM results are considered significantly different when P < 0.05.a Significant difference compared to control, b significant difference compared to methotrexate group

Figure 3: Effect of thymoquinone on intestinal tumor necrosis factor-alpha in methotrexate-induced intestinal toxicity in rats. Animal groups tested are control group, animals treated with thymoquinone alone, animals treated with methotrexate alone, or with methotrexate together with thymoquinone pre-treatment. Values are representation of 8 observations as means ± SEM results are considered significantly different when <i>P</i> < 0.05.a Significant difference compared to control, b significant difference compared to methotrexate group