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  Indian J Med Microbiol
 

Figure 1: Intestinal histopathological picture of rats treated with methotrexate, thymoquinone, and their combination. A photomicrograph of a section in rat intestine (H and E, ×100) of: (a and b) Control and thymoquinone-treated groups, respectively, showing a normal microscopic picture of intestinal villi. (c) Methotrexate-treated group shows intestinal architectural distortion with degenerated villi (black arrow) and crypt flattening (white arrow). (d) Methotrexate/thymoquinone group shows restored normal intestinal morphology, with only mild shortening of intestinal villi (gray arrow)

Figure 1: Intestinal histopathological picture of rats treated with methotrexate, thymoquinone, and their combination. A photomicrograph of a section in rat intestine (H and E, ×100) of: (a and b) Control and thymoquinone-treated groups, respectively, showing a normal microscopic picture of intestinal villi. (c) Methotrexate-treated group shows intestinal architectural distortion with degenerated villi (black arrow) and crypt flattening (white arrow). (d) Methotrexate/thymoquinone group shows restored normal intestinal morphology, with only mild shortening of intestinal villi (gray arrow)