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  Indian J Med Microbiol
 

Figure 4: Effects of MECA on cytokine production in CD mice. The levels of TNF-α, IFN-ã, IL-10, and IL-6 in ear tissues were measured using the cytometric bead array method. A total of 50 μg of tissue lysates were used to measure the cytokine levels. Every 2 days 30, 100, or 300 μg of MECA was painted onto each ear (4 times). Abbreviations are the same as in Figure 2. (a), TNF-α; (b), IFN-ã; (c), IL-10; (d), IL-6. All values are presented as the mean ± SD. #P < 0.05 and ##P < 0.01 vs. nontreated naïve mice (NOR); *P < 0.05 and **P < 0.01 vs. nontreated CD mice (CTL)

Figure 4: Effects of MECA on cytokine production in CD mice. The levels of TNF-α, IFN-ã, IL-10, and IL-6 in ear tissues were measured using the cytometric bead array method. A total of 50 μg of tissue lysates were used to measure the cytokine levels. Every 2 days 30, 100, or 300 μg of MECA was painted onto each ear (4 times). Abbreviations are the same as in Figure 2. (a), TNF-α; (b), IFN-ã; (c), IL-10; (d), IL-6. All values are presented as the mean ± SD. <sup>#</sup><i>P</i> < 0.05 and <sup>##</sup><i>P</i> < 0.01 vs. nontreated naïve mice (NOR); *<i>P</i> < 0.05 and **<i>P</i> < 0.01 vs. nontreated CD mice (CTL)