Pharmacognosy Magazine

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 12  |  Issue : 45  |  Page : 82--85

Bioactivities of ethanolic extract and its fractions of Cistus laurifolius L. (Cistaceae) and Salvia wiedemannii Boiss. (Lamiaceae) species


Osman Ustun1, Berrin-Ozcelik2, Turhan Baykal1 
1 Department of Pharmacognosy, Gazi University, 06330 Ankara, Turkey
2 Department of Pharmaceutical Microbiology, Gazi University, 06330 Ankara, Turkey

Correspondence Address:
Berrin-Ozcelik
Department of Pharmaceutical Microbiology, Gazi University, 06330 Ankara
Turkey

Background: Cistus laurifolius L. (Cistaceae) and Salvia wiedemannii Boiss. (Lamiaceae) have been used for treatment of some illnesses in Turkish folk medicine. In the present study, the ethanolic extract and its fractions obtained using re-extraction by hexane (Hx), chloroform (CHCl3), butanol, and remaining-water (r-H2O) of C. laurifolius were screened for their in vitro bioactivities. Materials and Methods: Activities were determined against both standard and the isolated strains of Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus, Enterococcus faecalis, as well as yeasts such as Candida albicans and Candida parapsilosis by microdilution method. Also, antiviral activity of C. laurifolius and S. wiedemannii extracts were tested on herpes simplex virus-1 (HSV-1) and parainfluenza-3 (PI-3) using Madin-Darby bovine kidney and vero cell lines. Results: Tested extracts of C. laurifolius (minimum inhibitory concentration 32 μg/mL) exerted a strong antimicrobial activity against Gram-negative bacteria of E. coli, P. mirabilis, K. pneumoniae, and A. baumannii. Conclusion: The Hx extract of C. laurifolius (cytopathogenic effect of 32–8 μg/mL) had antiviral activity on PI-3. Also, the r-H2O, CHCl3, and ethanol extracts (16–<0.25 μg/mL) of S. wiedemannii had significant antiviral activity on HSV-1, same as control.


How to cite this article:
Ustun O, BO, Baykal T. Bioactivities of ethanolic extract and its fractions of Cistus laurifolius L. (Cistaceae) and Salvia wiedemannii Boiss. (Lamiaceae) species.Phcog Mag 2016;12:82-85


How to cite this URL:
Ustun O, BO, Baykal T. Bioactivities of ethanolic extract and its fractions of Cistus laurifolius L. (Cistaceae) and Salvia wiedemannii Boiss. (Lamiaceae) species. Phcog Mag [serial online] 2016 [cited 2022 May 28 ];12:82-85
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2016;volume=12;issue=45;spage=82;epage=85;aulast=Ustun;type=0