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Use of in vitro assays to assess the potential antiproliferative and cytotoxic effects of saffron (Crocus sativus L.) in human lung cancer cell line

Samarghandian Saeed, Boskabady Mohammad Hossein, Davoodi Saideh

Year : 2010| Volume: 6| Issue : 24 | Page no: 309-314

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2 The role of Safranal and saffron stigma extracts in oxidative stress, diseases and photoaging: A systematic review
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3 Screening of Key Proteins Affecting Floral Initiation of Saffron Under Cold Stress Using iTRAQ-Based Proteomics
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5 Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells
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6 Novel and potent antimicrobial effects of caspofungin on drug-resistant Candida and bacteria
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Scientific Reports. 2020; 10(1)
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7 A comprehensive review of the pharmacological potential of Crocus sativus and its bioactive apocarotenoids
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8 Cytotoxicity test of binjai leaf (Mangifera caesia) ethanol extract in relation to Vero cells
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9 The waste of saffron crop, a cheap source of bioactive compounds
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10 Immunomodulatory perspectives of potential biological spices with special reference to cancer and diabetes
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11 A Representative Survey of Knowledge, Use, Perceived Benefits, Barriers, and Risks of Select Herbal Drugs Among Female Students in Gorgan City (Northeast Iran)
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12 Anti-tumor effects of crocetin and related molecular targets
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13 Determination of Antioxidant Properties of Six By-Products of Crocus sativus L. (Saffron) Plant Products
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14 Mitochondrial pathway mediated apoptosis and cell cycle arrest triggered by aqueous extract of wheatgrass in colon cancer colo-205 cells
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15 Effect of crocin on aged rat kidney through inhibition of oxidative stress and proinflammatory state
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16 The hepatoprotective effects of curcumin against drugs and toxic agents: an updated review
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18 Synthesis, characterization and in vitro evaluation of methotrexate conjugated fluorescent carbon nanoparticles as drug delivery system for human lung cancer targeting
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19 Crocus sativus L. (saffron) for cancer chemoprevention: A mini review
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20 Isolation and identification of ingredients inducing cancer cell death from the seeds of Alpinia galanga, a Chinese spice
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21 Preventive effect of safranal against oxidative damage in aged male rat brain
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22 Distinct Pro-Apoptotic Properties of Zhejiang Saffron against Human Lung Cancer Via a Caspase-8-9-3 Cascade
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23 Safranal, a Crocus sativus L constituent suppresses the growth of K-562 cells of chronic myelogenous leukemia. In silico and in vitro study
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24 Proposed cytotoxic mechanisms of the saffron carotenoids crocin and crocetin on cancer cell lines
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25 Antiproliferative activity and induction of apoptotic by ethanolic extract of Alpinia galanga rhizhome in human breast carcinoma cell line
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26 Achyranthes asperaRoot Extracts Induce Human Colon Cancer Cell (COLO-205) Death by Triggering the Mitochondrial Apoptosis Pathway and S Phase Cell Cycle Arrest
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27 Evaluation of Lung and Bronchoalveolar Lavage Fluid Oxidative Stress Indices for Assessing the Preventing Effects of Safranal on Respiratory Distress in Diabetic Rats
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28 Ameliorative Effect of Saffron Aqueous Extract on Hyperglycemia, Hyperlipidemia, and Oxidative Stress on Diabetic Encephalopathy in Streptozotocin Induced Experimental Diabetes Mellitus
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29 Chemo-immunotherapy using saffron and its ingredients followed by E7-NT (gp96) DNA vaccine generates different anti-tumor effects against tumors expressing the E7 protein of human papillomavirus
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30 Saffron and natural carotenoids: Biochemical activities and anti-tumor effects
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31 Cytotoxic Effect of Microbial Biosurfactants Against Human Embryonic Kidney Cancerous Cell: HEK-293 and Their Possible Role in Apoptosis
Arun Kumar Pradhan,Nilotpala Pradhan,Purusottam Mohapatra,Chanakya Nath Kundu,Prasanna Kumar Panda,Barada Kanta Mishra
Applied Biochemistry and Biotechnology. 2014;
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32 Safranal ameliorates antioxidant enzymes and suppresses lipid peroxidation and nitric oxide formation in aged male rat liver
Seyed Kazem Farahmand,Fariborz Samini,Mohammad Samini,Saeed Samarghandian
Biogerontology. 2013; 14(1): 63
[Pubmed]  [Google Scholar] [DOI]
33 Safranal ameliorates antioxidant enzymes and suppresses lipid peroxidation and nitric oxide formation in aged male rat liver
Farahmand, S.K. and Samini, F. and Samini, M. and Samarghandian, S.
Biogerontology. 2013; 14(1): 63-71
[Pubmed]  [Google Scholar]
34 Crocus sativus L. (Saffron) Stigma Aqueous Extract Induces Apoptosis in Alveolar Human Lung Cancer Cells through Caspase-Dependent Pathways Activation
Saeed Samarghandian,Abasalt Borji,Seyed Kazem Farahmand,Reza Afshari,Saeideh Davoodi
BioMed Research International. 2013; 2013: 1
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35 Plants vs. cancer: A review on natural phytochemicals in preventing and treating cancers and their druggability
Wang, H. and Khor, T.O. and Shu, L. and Su, Z.-Y. and Fuentes, F. and Lee, J.-H. and Kong, A.-N.T.
Anti-Cancer Agents in Medicinal Chemistry. 2012; 12(10): 1281-1305
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36 Extracellular caspase-8 dependent apoptosis on HeLa cancer cells and MRC-5 normal cells by ICD-85 (Venom derived peptides)
Mirakabadi, A.Z. and Sarzaeem, A.
Iranian Journal of Cancer Prevention. 2012; 5(4): 194-202
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37 Electrocardiogram alterations following one-week consumption of crocus sativus L. (saffron)
Joukar, S.
EXCLI Journal. 2012; 11: 480-486
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38 Nutrition in adult and childhood cancer: Role of carcinogens and anti-carcinogens
Mosby, T.T. and Cosgrove, M. and Sarkardei, S. and Platt, K.L. and Kaina, B.
Anticancer Research. 2012; 32(10): 4171-4192
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39 Contribution of selected medicinal plants for cancer prevention and therapy [Doprinos odabranih biljaka koje se koriste u medicinske svrhe u prevenciji i lečenju kancera]
Bachrach, Z.Y.
Acta Facultatis Medicae Naissensis. 2012; 29(3): 117-123
[Pubmed]  [Google Scholar]
40 Necrotic effect versus apoptotic nature of Camptothecin in human cervical cancer cells
Mirakabadi, A.Z. and Sarzaeem, A. and Moradhaseli, S. and Sayad, A. and Negahdary, M.
Iranian Journal of Cancer Prevention. 2012; 5(3): 109-116
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41 The suppression effects of desacetyluvaricin on hepatocellular carcinoma and its possible mechanism
Yu, J.Z. and Wu, X.-L. and Yu, B. and Dai, C.-Q. and Liu, K.-L. and Guo-Qiang, Q. and Zhou, G.X. and Lu, S.H. and Ju, D.H. and Chen, X.Y.
Pharmacognosy Magazine. 2012; 8(31): 225-230
[Pubmed]  [Google Scholar]
42 Crocus sativus L. (Iridaceae), saffron (II) [Crocus sativus L. (Iridaceae), le safran (II)]
Crozet, A.
Phytotherapie. 2012; 10(3): 186-193
[Pubmed]  [Google Scholar]
43 Crocus sativus L. (Iridaceae), le safran (II)
A. Crozet
Phytothérapie. 2012; 10(3): 186
[Pubmed]  [Google Scholar] [DOI]
44 Contribution of Selected Medicinal Plants for Cancer Prevention and Therapy
Zohara Bachrach
Acta Facultatis Medicae Naissensis. 2012; 29(3)
[Pubmed]  [Google Scholar] [DOI]
45 Litsea Deccanensis Ameliorates Myocardial Infarction in Wistar Rats: Evidence from Biochemical Histological Studies
P. Bharath Kumar,M. Mari Kannan,S. Darlin Quine
Journal of Young Pharmacists. 2011; 3(4): 287
[Pubmed]  [Google Scholar] [DOI]
46 Litsea deccanensis ameliorates myocardial infarction in wistar rats: Evidence from biochemical and histological studies
Bharath Kumar, P. and Mari Kannan, M. and Darlin Quine, S.
Journal of Young Pharmacists. 2011; 3(4): 287-296
[Pubmed]  [Google Scholar]


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