Cardioprotection

Saponins from Rhizoma Panacis Majoris attenuate myocardial ischemia/reperfusion injury via the activation of the Sirt1/Foxo1/Pgc-1α and Nrf2/antioxidant defense pathways in rats

He H-B, Li X-M, Li D-J, Ding Y-H, Zhang Y-F, Xu H-Y, et al.. Saponins from Rhizoma Panacis Majoris attenuate myocardial ischemia/reperfusion injury via the activation of the Sirt1/Foxo1/Pgc-1α and Nrf2/antioxidant defense pathways in rats. Pharmacognosy Magazine. 2018;14(56):297-307.

Steroidal saponin diosgenin from Dioscorea bulbifera protects cardiac cells from hypoxia-reoxygenation injury through modulation of pro-survival and pro-death molecules

Jayachandran KShanmugasu, A Vasanthi HRachel, Gurusamy N. Steroidal saponin diosgenin from Dioscorea bulbifera protects cardiac cells from hypoxia-reoxygenation injury through modulation of pro-survival and pro-death molecules. Pharmacognosy Magazine [Internet]. 2016;12(45s):s14-s20. https://www.ncbi.nlm.nih.gov/pubmed/27041852